243_253

Psychiatr. Pol. 2015; 49(2): 243–253

DOI: http://dx.doi.org/10.12740/PP/38250

Przemysław Bieńkowski, Dominika Dudek, Jerzy Samochowiec

FREE POLISH FULLTEXT:
W kierunku lepiej zaplanowanej nieselektywności: rola receptorów 5-HT7 w działaniu leku przeciwpsychotycznego II generacji – lurazydonu

FREE ENGLISH FULLTEXT:
Towards better non-selectivity: the role of 5-HT7 receptors in therapeutic efficacy of a second-generation antipsychotic – lurasidone

Summary
Effectiveness of currently available antipsychotic medications is far from satisfactory with many patients showing incomplete therapeutic response even after many trials with different antipsychotic drugs. Hence, there is an ongoing interest in searching for pharmacological mechanisms, which could potentiate therapeutic response to antipsychotic drugs and/or reduce its typical side effects. The primary aim of this mini-review is to summarize available evidence supporting the role of serotonin receptors, especially 5-HT7 receptors, in therapeutic effects of a second-generation antipsychotic drug, lurasidone.



ISSN 0033-2674 (PRINT)

ISSN 2391-5854 (ONLINE)


Psychiatria Polska
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