81_93
Psychiatr. Pol. 2015; 49(1): 81–93DOI: http://dx.doi.org/10.12740/PP/32923
Agnieszka Piróg-Balcerzak, Bogusław Habrat, Paweł Mierzejewski
FREE POLISH FULLTEXT:
Niewłaściwe używanie i nadużywanie kwetiapiny
FREE ENGLISH FULLTEXT:
Misuse and abuse of quetiapine
Abstract
Quetiapine is an atypical antipsychotic agent, frequently used in psychiatry, often for symptomatic treatment against a number of mental disorders differing from the registration indications. One of the use is to soothe the clinical conditions caused by the use of various psychoactive substances. The paper presents and discusses the reports of quetiapine misuse, abuse, and even mental addiction, as well as symptoms similar to the so-called discontinuation syndrome, often mixed with withdrawal syndrome occurring in the course of addiction. Most reports concern males, and especially those with a history of other psychoactive substance abuse, and personality disorders, often in conflict with the law. Therefore, clinicians should be cautious when prescribing quetiapine to such patients. The article discusses potential mechanisms responsible for quetiapine abuse. This is probably related to its sedative and anxiolytic activity which results in the frequent use with stimulants. Also, high affinity for the H1 receptor, as antihistamines agents causes rewarding action.
ISSN 0033-2674 (PRINT)
ISSN 2391-5854 (ONLINE)
Psychiatria Polska
is an Open Access journal:
Creative Commons: CC-BY
SHERPA RoMEO: Blue
is an Open Access journal:
Creative Commons: CC-BY
SHERPA RoMEO: Blue

Zadanie finansowane
w ramach umowy
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ze środków MNiSW
przeznaczonych
na działalność
upowszechniającą naukę
KRW PTP dziękuje
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za wsparcie finansowe
udzielone w 2020 roku
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